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My research is hoping to determine if there are any acute effects caused upon the human vasculature by electronic cigarette vapor. Volunteers for my study will be asked to visit the Cardio Vascular and Aging Laboratory here at the University of Texas for a total of 4 days. During their visit, volunteers will vape three different electronic cigarette products with a nominal amount of nicotine. Before and after their vape, I will test vascular function and stiffness utilizing valid and widely used measures; Flow Mediated Dilation and CAVI. Traditional cigarettes have been shown to negatively effect vascular function and stiffness acutely however the mechanisms remain unknown.
12-14% of individuals who try e-cigarettes become daily users. (Schoenborn and Gindi., 2015)
More than 20% of 18-24 year olds have tried e-cigs. (Schoenborn and Gindi., 2015).
Carnevale and colleagues discovered electronic cigarette vapor reduced arterial function during reactive hyperemia immediately following e-cigarette exposure. (Carnevale et al., 2016)
A 2016 study by Vlachopoulos et al., found that aortic stiffness and blood pressure both increased after electronic cigarette use in a sample of young smokers.
Tobacco has been linked to increased risk of heart disease and stroke. The inhalation of combusted chemicals leads to damage of the arterial wall which in turn leads to greater deposits of plaque.
At this level you will allow me to compensate 100% of the subjects needed for this study to have adequate statistical power.
